The Intestinal Transplant program at the Miami Transplant Institute has performed more than 450 intestinal transplants with 60% in infants and children with intestinal failure due to short bowel syndrome, dysmotility disorders, congenital enteropathies, and benign inoperable tumors. According to the Scientific Registry of Transplant Recipients, our one-year post-transplant survival is above national benchmarks, and we continue to improve yearly.
With the establishment of a multidisciplinary comprehensive Center for Intestinal Rehabilitation at MTI, as part of the initial evaluation, our physicians and team of experts strive to assure that an intestinal transplant is, in fact, indicated and that non-transplant options, such as autologous gastrointestinal reconstruction, have been exhausted prior to proceeding with transplantation.
If an intestinal transplant is indicated, by means of specialized testing, our experienced team determines which combination of organs best suits the patient’s illness. This may include an intestine-colon, modified multivisceral (stomach, pancreas, small bowel, and colon) or a multivisceral (liver, stomach, pancreas, small bowel, and colon) transplant. The team continues to apply techniques to prevent further life threatening complications of parental nutrition and loss of central vein access that may preclude a life-saving transplant.
During the pre-transplant period, our team’s transplant infectious disease specialists and immunologists tailor treatment regimens to decrease the likelihood of morbidity and mortality due to infection post-transplant. In the post-transplant period we have employed strict screening protocols to detect graft versus host disease early, in addition to an innovative treatment regimen.
Our goal is to improve the patient’s quality of life by being free of lines, tubes and ostomies either immediately post-transplant or early in the post-operative period. Our team has pioneered new surgical techniques including performing multivisceral transplants without an ostomy, performing isolated intestinal transplants with fake “hybrid” ostomy, and restoring bowel continuity in those with dysmotility disorders such as Hirschsprung’s by performing transplant colon pull-through procedures.
At MTI, children receive intestinal transplants with shorter operating times and less blood loss, which serve as indicators for better long-term outcomes. Our team is leading the field in developing new treatment regimens to salvage severe rejection if it were to occur and have instituted new immunosuppression regimens with aim to decrease chronic rejection and preserve organ function.
The Intestinal Transplant program at MTI has a multidisciplinary team of pediatric transplant surgeons, gastroenterologists, hepatologists, nurse coordinators, pharmacists, dieticians, speech therapists, social workers, and child life specialists that work together to provide excellence in supportive services and care to families while achieving great long-term outcomes.