For nearly 25 years, the Miami Transplant Institute’s Pediatric Liver Transplant Program has been taking care of children of all ages with end-stage liver disease awaiting transplantation as well as those with acute liver failure and post transplantation.
Through a multidisciplinary team of experts, which include hepatologists, surgeons, intensivists, anesthesiologists, interventional radiologists, infectious disease and ancillary staff (such as nursing, nutrition, pharmacy, social work, child life, psychology, physical/occupational therapy), the program at MTI is equipped to care for the most complex of cases in the pre-, peri- and post-transplant stages. The ultimate goal of this multidisciplinary team is to work together in conjunction with the patient’s family, to improve and renew the lives of children, and increase their access to transplantation. We offer innovative treatments such as therapeutic plasma exchange to stabilize patients in acute- and acute-on-chronic liver failure as they await a suitable donor. We also have been successfully performing liver transplants using alternative induction regimens to avoid complications of long-term steroids while decreasing the likelihood of organ rejection.
According to recent statistics from the Scientific Registry of Transplant Recipients (SRTR), the Pediatric Liver Transplant Program at MTI continues to be the largest and most experienced liver transplant program in Florida with outcomes surpassing national expectations. The program has helped nearly 700 children receive a second chance at life making it one of the top five programs nationwide. The surgical expertise available at MTI allows for transplantation not only of whole-, reduced-, and split-liver transplants, but also for combined organ transplants such as liver-kidney transplantation if deemed medically necessary. In the setting of acute liver failure as a result of a cause that may be reversible, our center has offered an auxiliary liver transplant – a partial liver from a donor that is temporarily placed to support the patient’s injured liver until their liver recovers. Our hepatobiliary surgeons are also versed in a variety of other surgical procedures including formation of portosystemic shunts for the treatment of portal hypertension as well as liver resections for hepatoblastoma.
MTI continues to move the field of pediatric liver transplantation forward by participating in several multicenter studies funded by the National Institute of Health (NIH) in the realm of adherence, post-traumatic stress in adolescents after transplantation, and Post-Transplant Lymphoproliferative Disease (PTLD). In addition, we are the only pediatric program in Florida providing alternative therapy for PTLD associated with Epstein-Barr virus (EBV) when conventional treatment fails.